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Table 2 Summary of the number of included males and females in recent studies with more than 100 participants that investigated the use of CPET for surgical risk assessment before major surgery

From: Why women are not small men: sex-related differences in perioperative cardiopulmonary exercise testing

Primary author, yearTarget populationSample sizeM/F% femalesSex-specific analysis
Older, 1993Patients older than 60 scheduled for major intra-abdominal surgeryn = 187NRNRNo
Older, 1999Patients scheduled for major intra-abdominal surgeryn = 548NRNRNo
Carlisle, 2007Patients after repair for unruptured AAAn = 167NRNRNo
Snowden, 2010Patients assessed for major surgery with low subjective functional capacityn = 171107/6437.4%No
Wilson, 2010Patients older than 55 assessed for colorectal, bladder, or kidney cancern = 847507/34040.1%Noa
Ausania, 2012Patients scheduled for pancreaticoduodenectomyn = 12467/5745.9%No
Colson, 2012Patients scheduled for major thoraco-abdominal surgeryn = 17251121/60435.0%No
Hartley, 2012Patients scheduled for elective AAA repairn = 415349/6615.9%No
Prentis, 2012Patients scheduled for elective AAA repairn = 185161/2412.9%No
Lai, 2013Patients scheduled for colorectal surgeryn = 269NRNRNo
Lee, 2013Patients scheduled for colorectal surgeryn = 11265/4742.0%No
Bernal, 2014Patients scheduled for liver transplant surgeryn = 223151/7232.3%Yes
Dunne, 2014Patients scheduled for liver surgeryn = 197138/5929.9%No
Neviere, 2014Patients scheduled for liver transplant surgeryn = 263198/6524.7%No
West, 2014Patients scheduled for major colonic surgeryn = 13689/4734.6%Yes
Grant, 2015Patients scheduled for elective AAA repairn = 506418/8817.4%No
Rose, 2018Patients scheduled for surgical treatment for colorectal cancern = 213126/8741.0%No
  1. aThe authors do note a male/female difference in the number of patients classified as “unfit” or “high-risk” and suggest that this should be looked at in further research. However, there was no separate analysis of outcome