Table 1 Summary of included randomized controlled trials
| Author | Year | Procedure | Number treatment/control | Intervention/control | Infusion duration | Type of anesthesia | Adverse events |
|---|---|---|---|---|---|---|---|
| De Oliveira et al. (De Oliveira et al., 2012) | 2012 | Gynecological laparoscopy | 35/35 |
1.5 mg/kg lidocaine bolus with 2 mg/kg/h infusion 0.9% normal saline | End of surgery | Sevoflurane | None |
| Dewinter et al. (Dewinter et al., 2016) | 2016 | Laparoscopic sterilization | 39/40 |
1.5 mg/kg lidocaine bolus with 1.5 mg/kg/h infusion 0.9% normal saline | 30 min after surgery | Sevoflurane | None |
| Lauwick et al. (Lauwick et al., 2008) | 2008 | Laparoscopic cholecystectomy | 25/24 |
1.5 mg/kg lidocaine bolus with 1.5 mg/kg/h infusion 0.9% normal saline | End of surgery | Desflurane | (1) Persistent hypertension, (1) rapid atrial fibrillation |
| McKay et al. (McKay et al., 2009) | 2009 | Laparoscopic endocrine/breast/gynecology/minor orthopedic | 29/27 |
1.5 mg/kg lidocaine bolus with 2 mg/kg/h infusion 1.5 mg/kg lidocaine bolus 0.9% normal saline infusion | 60 min after surgery |
Sevoflurane Desflurane Isoflurane | (1) Dizziness and visual disturbances |
| Ortiz et al. (Ortiz et al., 2016) | 2016 | Laparoscopic cholecystectomy | 21/22 |
1.5 mg/kg lidocaine bolus with 3 mg/kg/h infusion 0.9% normal saline infusion | 60 min after surgery | Isoflurane | None |